This WG will concentrate on the investigations both fundamental and applicative aspects of optical control of micro and nano particles and drops in isotropic and anisotropic fluidic environment. The approaches deal with the use of complex lightbeams, hydrodynamic and hermophoretic forces,optical and shape anisotropies of the objects. Innovative approaches to optofluidic trapping and manipulation will be investigated king use of the integrated photonic elements developed in WG1. New possibilities will be explored for the life sciences, particularly biomedical and chemical diagnostics based on the analysis and manipulation of particles in a fluidic environment.
The scientific workplan and achievements for WG2 activities will include:
- Complex light fields (i.e. spatially structured beams with intensity, phase and polarization management) to exert forces and torques at the micro and nano scale for complex control ofmotion and position of nano and micro-objects. The specific capabilities of light beams with tailored intensity, phase and/orpolarization distributions will be exploited to perform ad hoc tasks within integrated optofluidic devices. In addition, the use of reconfigurable devices, like spatial light modulators, can be incorporated to achieve specific light beam structures and switch among them at will.
- Optical tool-kit for sorting, stretching, squeezing, trapping, mixing of emulsion droplets for digital microfluidic applications (i.e., according to the optical beams configuration and to the element under testing, trapping and dragging of selected particles in specific positions of the microfluidic chip, mechanically stretching them, and exciting fluorescence and Raman signals from them will be explored).
- Optical forces for the development of tunable photonic devices in optofluidics platforms.
- Optical activation of chemical, physical and biological processes for contactless and sterile control and initiation of processes (i.e., novel strategies to trigger specific chemical reactions,or for the selective killing of cells, or for the stimulation of cell proliferation; micro-optofluidic implementation of systems to finely control the cell environment and to monitor the cell evaluation; etc.).
- Optically driven micro-flows. Light-driven micromechanics and microfluidics devices (i.e.optically guided micromotors, micropumps).
- Optical control in multifunctional platforms for biomedicine providing contactless diagnostics.
This WG will contribute to all objectives mentioned in part C which are related to its research topics.
Main expected achievements: Integration of optical manipulation concepts into exchangeable and portable microfluidic platforms. Prototypes of integrated optofluidic devices. Elemental and integrated bricks to build transportable optical lab-on-a-chip.