Dublin Institute of Technology, Ireland
Micro/Nanofibre Optical Sensors for Biomedical Applications
The increasing demand for rapid and reliable detection of certain biological molecules in life science research, drug discovery and medical applications has resulted in an increasing interest to biosensors and in particular to optical biosensors. Micro and nanofibre (MNF) based optical sensors have a number of intrinsic advantages over traditional analytical instruments such as rapid sensing speed, real-time monitoring capability, small footprint, low cost, high sensitivity, selectivity and immunity to electromagnetic interference.
Based on theoretical modelling and experimental verification this project will exploit the application of optical MNFs for measuring the change of parameters in the surrounding environment or binding phenomena on the surface of the fibre for biomedical applications. A reliable theoretical model will be set up and the structural parameters of the MNF based sensors, including the type of the MNF resonator, radius of a microfibre or diameter of a microsphere and the length of the coupling region will be optimized for higher sensitivity, wider dynamic range, and lower detection limit.
The proposed technique promises to be more sensitive in comparison with existing optical sensors. In addition the nanoscale size of the MNFs makes them suitable for practical applications that require very small quantities of samples.
WG2: Optical control in microfluidics